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Friday, February 23, 2007

Researchers with the University of Calgary in Canada have found that prolactin, a hormone produced during pregnancy, may reverse the progression of multiple sclerosis (MS), according to a paper published this week in The Journal of Neuroscience.

The study, led by Drs. Samuel Weiss and V. Wee Yong of the Hotchkiss Brain Institute, compared virgin and pregnant mice with MS-like lesions introduced by lysolecithin, a chemical which destroys the myelin sheaths around neurons. They found the pregnant mice developed smaller lesions and fewer damaged neurons, and showed signs of repaired neurons. They also found the pregnant mice had higher levels of cells called oligodendrocytes, which create myelin and are able to repair some damaged neurons through remyelination. Because prolactin regulates the levels of precursors of oligodendrocytes, the scientists hypothesized that prolactin levels were responsible for the differences in damage. They also tested virgin mice given additional prolactin, and found results similar to pregnant mice.File:Monthly multiple sclerosis MRI.gif

Previous studies have shown that other hormones could reduce myelin damage, but this is the first study to show a mechanism to reverse myelin damage, and establish an empirical connection between that mechanism and pregnancy. Dr. Weiss says, “It is thought that during pregnancy, women’s immune systems no longer destroyed the myelin. However, no previous study has tested whether pregnancy actually results in the production of new myelin, which may lead to improvement of symptoms. “We’re excited about this result because it suggests to us that prolactin has the potential to be used to enhance the production of new myelin.”

Dr. William McIlroy, national medical advisor for the Multiple Sclerosis Society of Canada, explains the significance of this study: “The results of this study should be well received by people living with MS today. It represents a new insight of how we might be able to reverse some of the effects of the disease and improve the quality of life for those who live under its influence.”File:Prolactin.png

Dr. Luanne Metz, director of the Calgary MS Clinic in the Department of Clinical Neurosciences, University of Calgary and Calgary Health Region, adds, “This discovery has the potential to take MS therapy a step further than current treatments that stabilize the disease in its early stages. By promoting repair, which is the goal of prolactin therapy, we have hope of actually improving symptoms in people with MS.”

Further animal studies need to be done to examine the possibility of side effects, such as lactation in men and non-pregnant women, as well as increased inflammation which could worsen the MS. Researchers believe human trials may begin within a few years.

Funding and support were provided by the Canadian Institutes of Health Research and the Multiple Sclerosis Society of Canada, the Alberta Heritage Foundation for Medical Research and the Stem Cell Network.

MS is an autoimmune disease of the central nervous system where the body attacks the fatty myelin which helps nerves carry electrical signals, causing muscle weakness and spasming which may lead to disability. MS affects approximately one of every 1000 people in North America, northern Europe and Australasia.

Tuesday, October 2, 2007

Ray Scott is running for the Family Coalition Party in the Ontario provincial election, in the Algoma-Manitoulin riding. Wikinews’ Nick Moreau interviewed him regarding his values, his experience, and his campaign.

Stay tuned for further interviews; every candidate from every party is eligible, and will be contacted. Expect interviews from Liberals, Progressive Conservatives, New Democratic Party members, Ontario Greens, as well as members from the Family Coalition, Freedom, Communist, Libertarian, and Confederation of Regions parties, as well as independents.

Saturday, April 23, 2005

Dermot Mannion has been named the new Chief Executive of Ireland’s national carrier, Aer Lingus. Mr. Mannion, 47, will take up the post in August 2005.

Aer Lingus almost went bankrupt in 2002, but a major cost-cutting effort by former CEO Willie Walshe lead to a dramatic turnaround in the airline’s fortunes, posting its largest ever profit in 2004. However, Willie Walshe left after a dispute with the government over privatization. He has since landed the top job at British Airways.

Mr. Mannion, an accountant, has extensive experience of aviation, having worked for the Dubai based airline Emirates since 1995. There he worked as Finance Director and later President of Group Support Services. He originally comes from County Sligo and is a graduate of Trinity College, Dublin.

Saturday, September 10, 2005

The American Red Cross is not lending its usual assistance in New Orleans, because the Louisiana National Guard acted first. After Saturday September 3, it was agreed with state officials the Red Cross was not needed because the large-scale evacuation of the city was under way.

The organization explains on its web site:

• Access to New Orleans is controlled by the National Guard and local authorities and while we are in constant contact with them, we simply cannot enter New Orleans against their orders.
• The state Homeland Security Department had requested–and continues to request–that the American Red Cross not come back into New Orleans following the hurricane. Our presence would keep people from evacuating and encourage others to come into the city.
• The Red Cross does not conduct search and rescue operations. We are an organization of civilian volunteers and cannot get relief aid into any location until the local authorities say it is safe and provide us with security and access.
• The original plan was to evacuate all the residents of New Orleans to safe places outside the city. With the hurricane bearing down, the city government decided to open a shelter of last resort in the Superdome downtown. We applaud this decision and believe it saved a significant number of lives.

On September 1, the Red Cross offered to Louisiana state officials to enter New Orleans, who rejected the offer due to logistical difficulties. Making the offer the next day to Col. Jay Mayeaux, the deputy director of the Louisiana Office of Homeland Security and Emergency Preparedness, the Red Cross was asked to wait 24 hours while preparations were made. By the next day, Saturday September 3rd, the National Guard had arrived in the city, felt they had adequate supplies and did not need the Red Cross.

Friday, March 20, 2009

Following the Pilkhana massacre which occurred February 25 and 26 leaving 74 dead and the inferno at the Bashundhara City shopping mall complex March 13 leaving seven dead, Prime Minister Sheikh Hasina said security measures are being tightened countrywide across Bangladesh.

Fire drills will be enacted at all key-point installations (KPI). Fire fighting systems will be examined by the fire brigade and the public works department (PWD) to ensure functionality. Security measures will be enhanced supplementing areas under private security such as at the Bashundhara City Complex.

The Fire Service and Civil Defence Department requires modernization and needs new equipment to fight fires past the sixth floor of buildings. The Fire Brigade says it needs turntable ladders, snorkels, foam-tenders, lighting units, emergency tenders, fireproof uniforms, and rescue ropes for fire fighting and rescue operations. Transportation to fires is also an issue due to narrow roads, low electrical wires and congestion.

The Bangladesh National Building Code requires fire fighting equipment installed in buildings over seven floors. This code is to be monitored by authorities to ensure compliance with the new guidelines and to make sure buildings are being maintained.

The Bashundhara City Complex opened Monday for shoppers two days after Friday’s blaze. A probe is underway to determine the cause of the fire and to assess structural damage.

Loss of life was minimized as the blaze broke out on a Friday, the beginning of the weekend in Bangladesh, so offices in the upper floors were empty. The lower eight floors are used for shopping and the upper floors are all Bashundhara Group offices.

The mall is valued at Tk 7.0 billion (US$100 million). It is not known if the complex is covered by fire insurance.

It is estimated that it will take over two years to rebuild the area damaged by flames which were burned down to a skeleton. Bashundhara City’s technical advisor, Latifur Rahman, estimated damages at Tk 2.0 billion (US$29m).

Only one television cameraman has been allowed in to film the burnt area. None of the 2,500 shops, cinemas or cafes were burnt by the inferno. The seventh and eighth floors still experience smoke damage, and there was water damage to merchandise.

A three member committee is currently investigating the cause of the fire which will consist of Iqbal Khan Chowdhury, joint secretary of the ministry, representatives of the police, IGP Noor Muhammad, and fire brigade, Director General Abu Nayeem Md Shahidullah. The committee is required to report within the week with their findings. The forensics department is also sifting through the burnt remains.

The Dhaka Chamber of Commerce and Industries has also formed a committee which has begun interviewing witnesses and recording their testimony alongside the government committee.

It has been discovered that 150 closed circuit cameras were not being used when the fire started. Another mystery is why the mall fire fighting system has been found unused.

“In the shopping mall there is an ultra-technology elevator which runs even without electricity but we have found that locked,” Iqbal Khan Chowdhury, joint secretary (Police) of the home ministry, said. “Why the fire burnt so fiercely is a matter to think. We have to see if there was any incendiary substance there. These matters seem to be mysterious.”

Mall management has been asked to submit substances and items which would have been in the upper floors when the fire started. The fire erupted on the 17th floor and spread quickly to the two floors above and engulfed the three floors below. The aerial ladders belonging to the Fire Service and Civil Defence reached as high as the 13th floor of the 21-storey building.

Videos have been sent to the United States (US) for examination to assist in determining the cause of the fire and to help in the damage assessment. Experts from the US are expected to arrive soon.

Firefighters were brought to the rooftop of the 20-storey tower by helicopter. The only fatality in this operation was Baki Billa, a firefighter of Bashundhara City firefighting department, who fell when climbing down a rope from a helicopter to the roof of the building. Three other firefighters made the transition safely. At this same time, the chief security officer was safely rescued by the Bangladesh Air Force helicopter, a Bell 212. Six security officers of the complex also lost their lives.

Sunday, April 3, 2005

Volunteers from across the United States and some foreign countries gathered Friday to start an unofficial border patrol project.

They converged on the town of Tombstone, Arizona to take part in what organizers call the Minuteman Project.

Many came with personal firearms, cell phones or walking canes.

Most estimates numbered the group at 400 to 450 people, recruited from the Internet, far less than the 1,300 the organizers had hoped for, but “it was enough to send a message,” according to Rep. Tom Tancredo, R-Colo.

“The federal government has walked away from this border,” he told some volunteers. He gained support and popularity for his stance against illegal immigration, but was characterized as anti-immigration in general.

“We are here to exercise what is a basic American right: free speech and the right to assemble,” he said.

Local citizens such as Luis Martinez, a third-generation Tombstone-area resident, were very unhappy with the developments. “They’ve come here to cause problems — to fight. Not to solve problems.

“I work in a ranch and all the ranchers use labor from the other side” of the border.

As Martinez fought back tears, he said he wanted to see the throngs leave Tombstone and go home.

During speeches delivered at orientation meetings, Rep. Tancredo was applauded loudly as he dismissed criticism from those who have called the volunteers racists and xenophobes. His fellow [[Republican Party (US)|Republican}}, President George Bush, described the group as “vigilantes.” Mexican President Vicente Fox used the term cazamigrantes — immigrant hunters.

Tancredo said: “We are saying to our government, ‘Please enforce the law,’ That is not a radical idea. That is not a vigilante idea. It is an American concept: the rule of law.”

Many of the volunteers, some from as far away as Italy, are bedding down in the nearby Miracle Valley Bible College for about $5 a night. Others are camping on the grounds of the run-down campus, about two miles north of the border.

Opposing sides were on the streets in Tombstone, although it appeared there was little contact or friction. Local, state and federal officers had mobilized in case confrontations arose.

James Gilchrist, a former Marine and a retired accountant from Aliso Viejo, Arizona, who ran the sign-up effort, said he expected more than 1,000 volunteers to help highlight the 30-day effort. The project’s goal is to patrol 23 miles of the San Pedro Valley, watch the border, and report illegal activity to law enforcement officials.

Many people fear that the project could result in vigilante violence. Organizers hope it causes the U.S. government to increase border patrols.

Tombstone is best known as the site of the 1881 shootout at the OK Corral.

Saturday, May 21, 2005

In an effort to ease complaints by the U.S. and Europe about a heavy influx of low priced Chinese goods, China will raise export tariffs on 74 categories of textile products in June. This follows plans from the U.S. to impose quotas on Chinese textiles and clothing.

Products likely to see an increase from the Chinese move include synthetic fiber shirts, trousers, knit shirts and blouses, cotton shirts, and combined cotton yarn. Last week, similar restrictions were imposed by the U.S. on cotton trousers, knit shirts, and underwear. Currently, a 2.5 cent charge per item is imposed; the new tariff will raise this to the equivalent of 12 cents per piece now. While this is a fourfold increase, it is not expected to affect consumer prices. Because of this, some doubt the tariff will have any effect on correcting the trade imbalance.

This move is in response to U.S. trade quotas imposed due to concerns that increased Chinese goods would put U.S. textile manufacturers out of business. According to Auggie Tantillo, executive director of the American Manufacturing Trade Action Coalition, a textile industry group in the U.S., the move will preserve 10,000 U.S. jobs. The new U.S. trade quota will limit the growth of Chinese textile imports to 7.5 percent compared with shipments over the past year.

Prior to January 1, a global quota system helped regulate the trade. With the quota system gone, fears have arisen that a flood of Chinese goods could undercut U.S. competitiveness in the market. China is able to market its goods cheaply due to an artificially weak yuan. The U.S. Treasury criticized the China yuan policy as “highly distortionary”, posing a major risk to China’s economy itself and to global economic growth. They challenged China to revalue its currency to bring it to a level they believe will allow fairer competition between global manufacturers.

China has disputed the charges of the U.S. Treasury. Chinese Commerce Minister Bo Xilai said, “I believe they are not reasonable”.

Laura Jones, a representative of large retailers, also criticized the move, saying “These restrictions on imports from China will do absolutely nothing to help the U.S. textile industry — and the government knows it.”

China has seen a boom in economic growth in recent years due to growing trade surpluses with the West, but economists worry that the trade gap will cause longer term global economic problems. China’s textile and apparel exports are the most noteworthy example, with exports up over 1,000 percent in some categories this year and the rapid loss of marketshare and jobs by U.S. textile manufacturers.

Beginning in 1978, the Chinese economy has been transforming from a Soviet-style centrally planned economy to more of a free market style system, under the rigid political control of Communist Party of China.

To this end, the government has leveraged foreign trade to stimulate economic growth. The result has been a fourfold increase in GDP, making China the sixth largest economy in the world. By 2012 the People’s Republic of China may have the highest GDP in the world.

According to U.S. statistics, from 1999 to 2004 China’s trade surplus with the U.S. doubled to $170 billion. Wal-Mart is China’s seventh largest export partner, just ahead of the United Kingdom.

However, the gains from their “socialist market economy” have not been without problems. The Chinese leadership has often experienced the worst results of socialism and capitalism: bureaucracy, lassitude, corruption, and inflation. Inflation rates have been an on-going challenge, reaching as high as 17% in 1995.

Environmental deterioration is a longer-term threat to economic growth. In 1998, the World Health Organization reported that China had seven of the 10 most-polluted cities on Earth. Another concern among some economists is that China’s economy is over-heating, and due to its global economic expansion this could have major repercussions among other nations.

Typically, wages have been low and working conditions poor, with workers living in restrictive dormitories and working at boring factory jobs. However, recent labor shortages have started improving conditions, and raising the minimum wage towards the equivalent of 100-150 US dollars per month. The labor shortages are in part a result of a demographic trend caused by strict family planning.

• “Economy of the People’s Republic of China” — Wikipedia, May 22, 2005
• “China raises tariffs on textile exports. Beijing hoping to counter criticism from U.S., Europe.” — CNN, May 21, 2005
• “China to increase export tariffs” — CNN, May 19, 2005